Immunoassay of insulin-like growth factor binding protein-1

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Immunoassay of insulin-like growth factor binding protein-1.

Accurate measurement of insulin-like growth factor (IGF) binding protein-1 (IGFBP-1) is important for precise definition of its physiological roles and potential diagnostic values. Because altered phosphorylation results in altered IGFBP-1 immunoreactivity, current assays may significantly underestimate or fail to detect physiological changes in the IGFBP-1 concentrations. We developed three EL...

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Vertex balding, plasma insulin-like growth factor 1, and insulin-like growth factor binding protein 3.

BACKGROUND A recent report suggested that men with vertex balding have higher levels of plasma insulin-like growth factor 1 (IGF-1). The association of its major carrier protein, insulin-like growth factor binding protein 3 (IGFBP-3), with male pattern hair loss has not been examined. OBJECTIVE We evaluated the relations of plasma concentrations of IGF-1 and IGFBP-3 with vertex balding in mid...

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Insulin-like growth factor-binding protein-1 and prostate cancer.

There is growing and persuasive evidence, both experimental (1–4) and epidemiologic (5–7), that the peptide hormone insulin-like growth factor-I (IGF-I) is a critical factor in the development of prostate cancer. Because of their central role in the regulation of bioavailable IGF-I, the insulin-like growth factor-binding proteins (IGFBPs) have also come under scrutiny as potential mediators of ...

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The Effect of 8 Weeks Resistance Training With Low Load and High Load on Testosterone, Insulin-like Growth Factor-1, Insulin-like Growth Factor Binding Protein-3 Levels, and Functional Adaptations in Older Women

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ژورنال

عنوان ژورنال: Clinical Chemistry

سال: 1997

ISSN: 0009-9147,1530-8561

DOI: 10.1093/clinchem/43.3.523